4.UNCAN.eu : A Coordination and Support Action to prepare UNCAN.eu platform

Work Programme : HORIZON

Type of Action : HORIZON-MISS-2021-UNCAN-01

Budget €3M

Project duration : 01 September 2022 – 01 December 2023 (15 months)

Lead Coordinator : Inserm, France

Contact : Be_EBCP@sciensano.be, Marc Van Den Bulcke, Hélène Antoine-Poirel

Website : https://uncan.eu/

Main objectives

The 15-month coordination and support action “4.UNCAN.eu” will generate a strategic agenda to launch UNCAN.eu, a European initiative to UNderstand CANcer proposed by the Mission Board and the European Beating Cancer Plan. This research agenda will be built with the final aim of achieving a new breakthrough in cancer prevention and treatment that will contribute to saving European citizens’ lives and help ensuring an optimal quality of life to disease survivors.

To reach a new level of understanding, UNCAN.eu will take advantage of recent advances in research data generation and data sciences. Reliable, high-quality cancer research data generated by experimental model analysis and collected from longitudinal follow-up of cancer patients will be shared and integrated at an unprecedented scale within a Federated Cancer Research data hub, in the context of the General Data Protection Regulation.

This information will be used by relevant players in Europe and beyond to address urgent and essential scientific and medical challenges in cancer prevention, early diagnosis, treatment and survivorship, in males and females of various ages. These challenges, identified in close interaction with European patients and citizens, will be tackled through competitive, ambitious and innovative, cross-border and trans-disciplinary research programmes built in a problem-solving manner.

The definition of challenges will integrate inequalities in cancer research across regions and member states in order to boost the research potential of less-developed regions in Europe. Players will be committed to open science principles, including FAIR (findable, accessible, interoperable, and reusable) guiding principles for scientific data collection, management and stewardship. The new understanding gained from the collection and analysis of this wealth of data will apply secondarily to other diseases.



  • 22 Countries
  • 29 partners

Belgian partners

  • Sciensano
  • Institut Jules Bordet
  • UZ Leuven


  • WP1 : Coordination and management (INSERM, France)
  • WP2 : Identification of cancer research challenges to address future EU priorities & research policies (CIBER, Spain)
  • WP3 : Mapping of European Research Infrastructures and initiatives Roadmap for a European Federated Cancer Research Data Hub (DKFZ, Germany)
  • WP4 : Patients and European Citizens in cancer research (ECPC, Belgium)
  • WP5 : Governance, organization, logistics, finances, and sustainabilitys (ACC, Italy)
  • WP6 : Inequalities in cancer research – improved science with improved outreach  (OOI, Hungary)


  • Cancer Research Challenges
  • Federated Cancer Data Hub


Autres projets

ECHoS : Establishing of Cancer Mission Hubs: Networks and Synergies

PREHDICT : Health-economic modelling of PREvention strategies for Hpv-related DIseases in European CounTries

Haute Autorité de la Santé (France) : Soutien à l'introduction du dépistage HPV

EU-TOPIA : “TOwards imProved screening for breast, cervical and colorectal cancer In All of EUrope”

Centre for Disease Control (USA) : Mises à jour des revues systématiques

CoheaHr : Comparing health services interventions for the prevention of HPV-related cancer

HPV OncoPredict (Horizon 2020)

Unité Epidémiologie Cancer HPV OncoPredict (Horizon 2020)


Unité Epidémiologie Cancer Triage HPV AUSTRALIA

Healthy Cloud : Health Research & Innovation Cloud

PERCH : PartnERship to Contrast HPV

Unité Epidémiologie Cancer PERCH : PartnERship to Contrast HPV

GDI : Genomic Data Infrastructure

European Health Data Space GDI : Genomic Data Infrastructure

JANE : Joint Action on European Networks of Expertise

CanScreen-ECIS : Strengthening Cancer Screening data collection to update European Cancer Information System and improve quality and coverage of cancer screening programmes in Europe

CAN.HEAL, Building the EU Cancer and Public Health Genomics : Action grants for ‘Cancer Diagnostic and Treatment for All’ including ‘Genomic for Public Health’


eCAN : Joint Action on strengthening ehealth including telemedicine and remote monitoring for health care systems for cancer prevention and care

CRaNE : Joint Action on EU Network of Comprehensive Cancer Centres

B1MG : B1+M Genomes