EU-TOPIA : “TOwards imProved screening for breast, cervical and colorectal cancer In All of EUrope”

EU-TOPIA : “TOwards imProved screening for breast, cervical and colorectal cancer In All of EUrope”

Breast, cervical and colorectal cancer cause more than 250,000 deaths each year in Europe. This represents 20% of overall cancer mortality. While substantial progress has been made in the detection and treatment of these cancers, there is a persisting inequality in cancer burden across European countries.

Screening has been introduced in several European countries in an effort to reduce cancer burden. However, these programmes vary considerably and the long-term effectiveness of screening has only been assessed in a few. In an effort to identify opportunities to improve cancer outcomes across Europe, EU-TOPIA (Towards improved screening for breast, cervical and colorectal cancer in all of Europe), a five year project (2015-2020) funded by the European Commission’s Horizon 2020 programme, is now underway.


EU-TOPIA aims to systematically evaluate and quantify the harms and benefits of screening programmes for breast, cervical, and colorectal cancer in all European countries. Armed with this important information, we hope to identify ways to improve health outcomes and increase equity.

EU-TOPIA will lead to

  • reduced inequity in cancer burden
  • fewer cancer deaths
  • less over-diagnosed cases
  • improved quality of life
  • more cost-effective cancer screening programmes

Using a health-policy cycle approach, EU-TOPIA, in consultation with screening researchers from across Europe, will develop key quality indicators to quantify the benefits and harms of screening and develop country-specific decision models to estimate the long-term harms and benefits of screening.

We will create three web-based tools (monitoring, model-quantification and barrier assessment) that will support researchers and policy makers to develop, implement, evaluate and monitor existing or future screening programs within their country. These tools will be presented at four workshops and can be used by country representatives (researchers and policymakers) for self-evaluation of screening.


Autres projets

ECHoS : Establishing of Cancer Mission Hubs: Networks and Synergies

Centre for Disease Control (USA) : Updates voor systematische reviews

PREHDICT : Health-economic modelling of PREvention strategies for Hpv-related DIseases in European CounTries

Haute Autorité de la Santé (Frankrijk): Ondersteuning voor de introductie van HPV-screening

CoheaHr : Comparing health services interventions for the prevention of HPV-related cancer

HPV OncoPredict (Horizon 2020)

Unit Cancer Epidemiology HPV OncoPredict (Horizon 2020)


Unit Cancer Epidemiology Triage HPV AUSTRALIA

Healthy Cloud : Health Research & Innovation Cloud

JANE : Joint Action on European Networks of Expertise : A Coordination and Support Action to prepare platform

PERCH : PartnERship to Contrast HPV

Unit Cancer Epidemiology PERCH : PartnERship to Contrast HPV

CAN.HEAL, Building the EU Cancer and Public Health Genomics : Action grants for ‘Cancer Diagnostic and Treatment for All’ including ‘Genomic for Public Health’

CanScreen-ECIS : Strengthening Cancer Screening data collection to update European Cancer Information System and improve quality and coverage of cancer screening programmes in Europe

GDI : Genomic Data Infrastructure

European Health Data Space GDI : Genomic Data Infrastructure


eCAN : Joint Action on strengthening ehealth including telemedicine and remote monitoring for health care systems for cancer prevention and care

CRaNE : Joint Action on EU Network of Comprehensive Cancer Centres

B1MG : 1+M Genomes